Roundup® a Carcinogen? Never Mind the Science…

weeds

Today, the International Agency for Research on Cancer (IARC) has departed from the scientific consensus to declare glyphosate, the active ingredient in Roundup®, to be a class 2A “probable human carcinogen”. This contradicts a strong and long standing consensus supported by a vast array of data and real world experience, and comes from an organization that rarely addresses potential pesticide carcinogenicity, perhaps because the real concerns in this area are minimal, and lie elsewhere. The IARC statement is not the result of a thorough, considered and critical review of all the relevant data. It is beyond the pale.

A vast body of relevant information, including dozens of detailed genotoxicity, studies, animal bioassays, peer-reviewed publications and regulatory assessments, that show no evidence of carcinogenicity, and confirm its safety were presented to the IARC, but seem to have been ignored. On the other hand, witnesses report one paper so severely criticized and discredited that it was condemned by the scientific community and withdrawn by the publisher was actually taken on board by IARC.

That the IARC seems to have even considered such a fatally flawed and withdrawn paper triggers the Séralini Rule: “If you favorably cite the 2012 Séralini rats fed on Roundup® ready maize study, you just lost the argument.” The fact that IARC seems to be taking seriously this laughingstock publication suggests they have run thoroughly off the rails, gone beyond anything defensible as science, and well into fictional realms.

Scientific experts who have considered the body of relevant research do not agree with a categorization of glyphosate as carcinogenic for a very simple reason – it’s clearly not. There is nothing in the data to support such claims, and nothing in the deep reservoir of real world experience with glyphosate, to justify such a move. IARC did not consider any new research or data, and all the information they considered has already been evaluated by regulatory bodies around the world. The most recent of these reviews was conducted by Germany on behalf of the European Union.

IARC, a semi-autonomous “extension” of the World Health Organization, has been criticized before for advancing unsupportable conclusions reached using flawed methodology. But IARC’s assault on glyphosate breaks new ground, which is all the more ironic given its clearly superior safety profile compared to the likely alternatives. Glyphosate lacks the chemical structural characteristics of known carcinogens, and neither IARC nor anyone else has ever offered an even remotely plausible mechanism of carcinogenicity. No new data have been advanced to support this categorization, which can be reached only by ignoring and defying a vast body of data and experience. One might be forgiven for suspecting the intrusion of politics into the process; a suspicion not weakened by noting that one of the participants is employed by the Environmental Defense Fund, an organization of professional campaigners that has recently faced charges of manufacturing chemophobic alarms without scientific basis.

It seems IARC is in dire need of some adult supervision. Whether or not WHO finds the bureaucratic courage to apply such, and correct this policy miscarriage, remains to be seen. If they don’t will IARC start picking off the entire list of agrochemicals?

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About the author

L. Val Giddings is a senior fellow at ITIF with three decades of experience in science and regulatory policy relating to biotechnology innovations in agriculture and biomedicine. He is also president and CEO of PrometheusAB, Inc., providing consulting services on biotechnology issues to governments, multilateral organizations, and industry clients. Before founding PrometheusAB, he served eight years as vice president for food and agriculture at the Biotechnology Industry Organization and a decade as a regulatory official with the U.S. Department of Agriculture. Giddings received his Ph.D. in genetics and evolutionary biology from the University of Hawaii in 1980.
  • First Officer

    Not sure they actually cite Seralini’s work even if they may have considered it. But i haven’t checked the citings in the citings.

    Still, where are all the cancer incidence increases? http://seer.cancer.gov/statfacts/html/nhl.html

    From their statement:

    “1 International Agency for Research on Cancer
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    5 Waddell BL, Zahm SH, Baris D, et al. Agricultural
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    6 McDuffi e HH, Pahwa P, McLaughlin JR, et al.
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    7 Eriksson M, Hardell L, Carlberg M, Akerman M.
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